Detalhe da pesquisa
1.
Phase 1 trial of navitoclax and sorafenib in patients with relapsed or refractory solid tumors with hepatocellular carcinoma expansion cohort.
Invest New Drugs
; 42(1): 127-135, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38270822
2.
A phase 1 trial utilizing a pharmacokinetic endpoint to determine the optimal dose of ramucirumab in children and adolescents with relapsed or refractory solid tumors, including central nervous system tumors.
Pediatr Blood Cancer
; 71(3): e30817, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38189770
3.
A phase 1/2 study of pepinemab in children, adolescents, or young adults with recurrent or refractory solid tumors: A children's oncology group consortium report (ADVL1614).
Pediatr Blood Cancer
; 71(6): e30938, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38520670
4.
Pediatric phase 2 trial of a WEE1 inhibitor, adavosertib (AZD1775), and irinotecan for relapsed neuroblastoma, medulloblastoma, and rhabdomyosarcoma.
Cancer
; 129(14): 2245-2255, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37081608
5.
Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism.
Drug Metab Dispos
; 51(2): 183-192, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36351835
6.
Feasibility of pevonedistat combined with azacitidine, fludarabine, cytarabine in pediatric relapsed/refractory AML: Results from COG ADVL1712.
Pediatr Blood Cancer
; 70(12): e30672, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37710306
7.
Sorbitol Is a Severity Biomarker for PMM2-CDG with Therapeutic Implications.
Ann Neurol
; 90(6): 887-900, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34652821
8.
Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies.
Invest New Drugs
; 40(1): 115-123, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34515877
9.
Combined local delivery of tacrolimus and stem cells in hydrogel for enhancing peripheral nerve regeneration.
Biotechnol Bioeng
; 118(7): 2804-2814, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33913523
10.
A phase 1 study of prexasertib (LY2606368), a CHK1/2 inhibitor, in pediatric patients with recurrent or refractory solid tumors, including CNS tumors: A report from the Children's Oncology Group Pediatric Early Phase Clinical Trials Network (ADVL1515).
Pediatr Blood Cancer
; 68(9): e29065, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33881209
11.
A phase 1 study of entinostat in children and adolescents with recurrent or refractory solid tumors, including CNS tumors: Trial ADVL1513, Pediatric Early Phase-Clinical Trial Network (PEP-CTN).
Pediatr Blood Cancer
; 68(4): e28892, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33438318
12.
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Lancet Oncol
; 21(4): 541-550, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32192573
13.
Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer.
Breast Cancer Res
; 22(1): 51, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32430040
14.
ADVL1522: A phase 2 study of lorvotuzumab mertansine (IMGN901) in children with relapsed or refractory wilms tumor, rhabdomyosarcoma, neuroblastoma, pleuropulmonary blastoma, malignant peripheral nerve sheath tumor, or synovial sarcoma-A Children's Oncology Group study.
Cancer
; 126(24): 5303-5310, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32914879
15.
Phase 1/2 trial of talazoparib in combination with temozolomide in children and adolescents with refractory/recurrent solid tumors including Ewing sarcoma: A Children's Oncology Group Phase 1 Consortium study (ADVL1411).
Pediatr Blood Cancer
; 67(2): e28073, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31724813
16.
Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in CYP2C9 and CYP2C19.
Drug Metab Dispos
; 47(4): 425-435, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745309
17.
Vaginal Diazepam for Nonrelaxing Pelvic Floor Dysfunction: The Pharmacokinetic Profile.
J Sex Med
; 16(6): 763-766, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010782
18.
A study of axitinib, a VEGF receptor tyrosine kinase inhibitor, in children and adolescents with recurrent or refractory solid tumors: A Children's Oncology Group phase 1 and pilot consortium trial (ADVL1315).
Cancer
; 124(23): 4548-4555, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30394521
19.
Phase 1 trial of ontuxizumab (MORAb-004) in children with relapsed or refractory solid tumors: A report from the Children's Oncology Group Phase 1 Pilot Consortium (ADVL1213).
Pediatr Blood Cancer
; 65(5): e26944, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29292843
20.
A phase 1 study of eribulin mesylate (E7389), a novel microtubule-targeting chemotherapeutic agent, in children with refractory or recurrent solid tumors: A Children's Oncology Group Phase 1 Consortium study (ADVL1314).
Pediatr Blood Cancer
; 65(8): e27066, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29719113